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Ультразвуковая доставка лекарственных веществ

Авторы: Ли Е.С., Беликов Н.В., Скалеух Е.Д.
Опубликовано в выпуске: #1(96)/2025
DOI:


Раздел: Медицинские науки | Рубрика: Медицинское оборудование и приборы

Ключевые слова: ультразвук, адресная доставка лекарств, кавитация, химиотерапия, доставка белков, доставка генотерапевтических препаратов, газонаполненные микропузырьки, наноносители

Опубликовано: 18.02.2025

Одна из основных проблем на пути внедрения новых лекарственных средств в клиническую практику — сложность доставки препарата в целевые клетки. Стремительно возрастает роль ультразвука в доставке терапевтических агентов, включая генетический материал, белки и химиотерапевтические агенты. Поскольку ультразвуковое воздействие представляет собой широкодоступный и относительно недорогой метод, такую доставку лекарственных средств можно считать перспективным подходом к лечению некоторых заболеваний. В работе рассмотрены методы ультразвуковой доставки различных лекарственных веществ и принципы, лежащие в их основе, составлена их классификация по типу молекул и рассмотрены некоторые органы и ткани с точки зрения возможностей и перспектив применения ультразвуковой импрегнации.


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